Coronavirus

Don’t rely on a negative test result to see your family for Thanksgiving

Reading, PA - October 13: A man gets swabbed by CNA Keila Kelley. At the state run free COVID-19 testing site setup on Front Street in Reading, PA outside FirstEnergy Stadium Tuesday morning October 13, 2020. The site will be there for 5 days and was setup in response to an increase in cases in Berks County. (Photo by Ben Hasty/MediaNews Group/Reading Eagle via Getty Images)

(CNN) — If you think a negative test result means you don’t have coronavirus, you could be wrong.

It can take days before a new infection shows up on a COVID-19 test.

“We know that the incubation period for COVID-19 is up to 14 days. And before that, you can be testing negative, and have no symptoms,” emergency medicine physician Dr. Leana Wen said.

“But you could actually be harboring the virus and be able to transmit it to others.”

So if you want to get tested before seeing friends or family, here’s what you need to know:

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If I got infected yesterday, would a test today pick that up?

Probably not. A study in the medical journal Annals of Internal Medicine examined false-negative test results of people who actually had COVID-19.

The study estimated that during four days of infection before symptoms typically started, the probability of getting an incorrect/negative test result on Day 1 was 100%.

On the day people started showing symptoms, the average false-negative rate had dropped to 38%, according to the study. Three days after symptoms started, the false-negative rate dropped to 20%.

“The virus just takes time to replicate in the body to detectable levels,” said Justin Lessler, a senior author of the study and associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health.

“You can get infected by just a few viral particles, but these will not be detectable until they have time to replicate to adequate levels to be detected,” he told CNN by email.

So how many days should a person wait after possible exposure to get tested?

“There is no hard and fast rule, but the evidence suggests getting a test before the third day after exposure is not of much use,” Lessler said.

Could I be contagious while testing negative?

Absolutely. “People sort of feel like if you test (negative), you’re out of the woods. And you’re kind of not,” said Dr. Rochelle Walensky, chief of the infectious diseases division at Massachusetts General Hospital.

For people who get sick with COVID-19, symptoms can take up to two weeks to appear, but the average time is about five days, Walensky said.

“It’s generally thought that you’re most infectious the two days before that day and the two days after that,” she said.

One reason why this virus spreads so easily is because people can be infectious without any symptoms. The US Centers for Disease Control and Prevention estimates 40% of infections are asymptomatic, and 50% of transmissions happen before symptoms begin.

“It’s been among the biggest Achilles’ heels of this. And it’s been among the biggest challenges and the unexpected things because (with) its cousins, this is not true,” Walensky said.

“The reason we were able to control the SARS outbreak so quickly — although there were obviously a lot of deaths there — but it didn’t turn into a pandemic is because people weren’t shedding (the virus) until they got symptoms.”

Do different COVID-19 tests matter?

There are two main types of diagnostic tests that try to detect whether you have an active coronavirus infection:

Molecular tests, such as PCR tests, look for the virus’ genetic material. Most of these tests are performed with nasal swabs or throat swabs, though some can be done using saliva, the US Food and Drug Administration says.

“This test is typically highly accurate and usually does not need to be repeated,” the FDA says.

But the downside to molecular testing is that results can take a while — anywhere from the same day to one week after testing.

“For people who show symptoms, so far the studies show the accuracy of the molecular test to find a positive case increases with each day after the exposure,” said Pia MacDonald, infectious disease epidemiologist at the nonprofit research institute RTI International.

But for infected people who don’t get symptoms, the accuracy rates are less clear, she said. “Molecular test performance studies on asymptomatic people are very limited.”

Antigen tests are often known as rapid tests (though some molecular tests are rapid, too). Antigen tests are not antibody tests, which tell you whether you’ve previously had the virus and have already developed antibodies against the infection.

Antigen tests don’t look for the virus’ genetic material, like molecular tests do. Instead, they look for specific proteins on the surface of the virus.

The good news is you can get antigen test results in less than an hour. The bad news is you’re more likely to get a false negative with a rapid antigen test.

“Positive results are usually highly accurate but negative results may need to be confirmed with a molecular test,” the FDA says.

“Antigen tests are more likely to miss an active coronavirus infection compared to molecular tests.”

This could help explain some of the recent spread of COVID-19 linked to the White House.

While staff members close to President Donald Trump and Vice President Mike Pence are frequently tested, White House staffers often use rapid antigen tests, which generally have a higher rate of false negatives than molecular tests do.

Regardless of which type of diagnostic test you use, you’re generally more likely to get a false negative than a false positive.

“If a molecular test is positive, it’s an accurate reflection of a person being infected,” MacDonald said.

“If it’s negative, it’s less reliable that the person is indeed negative. The same is true of the antigen tests.”

Can I test myself at home?

Yes. There are some at-home testing kits available, such at the Everlywell COVID-19 molecular test. Users take their own nasal swab samples and mail them to a lab, which will send results digitally within 24 to 48 hours of receiving the samples.

But taking any kind of COVID-19 test too early might miss an infection, said Dr. Frank Ong, chief medical and scientific officer at Everlywell.

“As testing capacity has continued to increase, more and more asymptomatic or mildly symptomatic individuals have undergone testing, most of whom likely have lower viral loads in their clinical samples,” he said.

So what should I do if I want to see friends or relatives?

If you insist on seeing anyone who doesn’t live with you, self-quarantining for 14 days beforehand is best, Walensky said.

“If you do that properly, you don’t need a test,” she said. “That’s probably the cleanest way to do it.”

To be clear: Quarantining means staying home. It does not mean you can run errands.

“‘Grocery store’ and ‘quarantine’ don’t belong in the same sentence,” Walensky said.

Lessler agreed that quarantining is best, and any testing must be done intelligently.

“If you are visiting an elderly family member and have a reasonable risk of having been exposed, there is no substitute for 14 days of quarantine,” Lessler said.

“At the very least I would wait 10 days (of quarantining) and have a negative test,” he said.

“If you are visiting a younger, healthy family member and have little chance of being exposed before or during travel, then 5 or 7 days (of quarantine) plus a negative test is probably plenty of risk reduction, though no guarantee of safety.”

What should I do after testing negative?

It’s important to strictly quarantine not just before your COVID-19 test, but after your test as well.

“You should definitely remain in quarantine while awaiting test results and make sure everyone you are getting together with is on the same page about the plan for controlling infection risk,” Lessler said.

There have already been cases of coronavirus spread within families just days after a person tested negative, said Dr. Michael St. Louis, a member of the CDC’s Community Guidance Team.

He said everyone must remember to treat family from different households the same way you would treat unrelated friends or work colleagues during this pandemic.

What’s the safest way to celebrate Thanksgiving?

The best way to help make sure everyone stays healthy is to celebrate the holidays remotely.

“I have three kids. … And my parents are not going to be joining us this year,” Walensky said.

“It’s just awful. But what I really hold out for is that my parents are pretty healthy, and I would never forgive myself if I put them in harm’s way. And I’m just looking forward to a 2021 when we can be together.”

The CDC suggests celebrating with loved ones virtually online. You can also make traditional Thanksgiving dishes and deliver them “in a way that doesn’t involve contact” to relatives, neighbors or those who might be feeling lonely.

Walensky said the small sacrifices made this Thanksgiving will help ensure everyone will be healthy enough to sit at the table next year.

“At least they’ll be there next year, whereas irresponsible behavior now might mean they won’t be here later,” she said.

“Let’s do this so that we can have a much better shot of being around the table together, healthy, in 2021.”

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Indiana coronavirus timeline

With information from the Indiana Department of Health through Nov. 30, this timeline reflects updated tallies of deaths and positive tests prior to that date.

  • March 6: Indiana State Department of Health (ISDH) confirms the first case in Indiana. Officials say the Marion County resident had recently traveled to Boston to attend a BioGen conference as a contractor.
  • March 8: ISDH confirms a second case. An adult in Hendricks County who had also traveled to the BioGen conference was placed in isolation. Noblesville Schools say a parent and that parent’s children will be self-quarantining after attending an out-of-state event where someone else tested positive.
  • March 9: Avon Community School Corp. says a student on March 8 tested positive.
  • March 10: ISDH launches an online tracker. Ball State University basketball fans learn the Mid-American Conference tourney will have no fans in the stands. Three businesses operating nursing homes in Indiana announce they will no longer allow visitors.
  • March 11: The Indianapolis-based NCAA announces the Final Four basketball tournaments will be conducted with essential staff and limited family attendance. The Big Ten announces all sports events, including the men’s basketball tournament at Bankers Life Fieldhouse, will have no fans starting March 12. Ball State University suspends in-person classes the rest of the spring semester. NBA suspends all games, including the Indiana Pacers, until further notice. Butler University and the University of Indianapolis extend spring break, after which they will have virtual classes.
  • March 12: Gov. Eric Holcomb announces new protections that led to extended public school closings and the cancellation of large events across the state. The NCAA cancels its basketball tournaments. The Big Ten suspends all sporting events through the winter and spring seasons. The league including the Indy Fuel hockey team suspends its season. Indy Eleven says it will reschedule four matches. Indianapolis’ annual St. Patrick’s Day Parade is canceled. 
  • March 13: The Indiana High School Athletic Association postpones the boys basketball tournament. Wayzata Home Products, a Connersville cabinet maker, shuts down and lays off its entire workforce due to market uncertainty. Gov. Holcomb announces actions including the elimination of Medicaid co-pays for COVID-19 testing and the lifting of limits on the number of work hours per day for drivers of commercial vehicles. Franklin College says it will begin online classes March 18 and empty residence halls of students in two days. The Children’s Museum of Indianapolis closes indefinitely. The Indianapolis Public Library joins other libraries across Indiana and closes all facilities indefinitely.
  • March 14: The Indiana Gaming Commission says all licensed gaming and racing operations will close in two days for an indefinite period.
  • March 15: Indiana had its first death. St. Vincent Hospital in Indianapolis announces it will suspend all elective, non-urgent surgeries.
  • March 16: Indiana had its second death. Gov. Holcomb announced the first Hoosier death. He closes bars, restaurants and nightclubs to in-person patrons, but maintains carryout and delivery services.
  • March 17: Indiana had its third and fourth deaths. ISDH announces Indiana’s second death. Indiana’s Catholic bishops cancel masses indefinitely. Gov. Holcomb activates the National Guard. Purdue, Butler and Indiana State universities cancel May commencement ceremonies.
  • March 18: Indiana had its fifth death. Eli Lilly and Co. says it will use its labs to speed up testing in Indiana. The 500 Festival suspends all events. Simon Property Group closes all malls and retail properties.
  • March 19: Gov. Holcomb extends Indiana’s state of emergency into May. Holcomb says he’ll close all K-12 public and nonpublic schools. Standardized testing was canceled. The state’s income-tax and corporate-tax payment deadline was extended to July 15. Holcomb says the state will waive job search requirements for people applying for Temporary Assistance to Needy Families. The IHSAA Boys Basketball State Tournament was canceled. The Marion County Emergency Operations Center upgrades to Level 1 status.
  • March 20: Indiana’s death toll rose to 9. ISDH announces Indiana’s third death. Gov. Holcomb moves the state’s primary election to June 2. Indiana University says it is postponing May commencement ceremonies on all campuses.
  • March 21: Indiana’s death toll rises to 14. ISDH announces Indiana’s fourth death. Indiana National Guard says it and the Department of Transportation are distributing medical supplies to hospitals.
  • March 22: Indiana’s death toll rises to 19. ISDH announces seven deaths.
  • March 23: Indiana’s death toll rises to 24. Holcomb orders Hoosiers deemed nonessential to “stay at home” from March 24-April 7. Eli Lilly & Co. begins drive-thru testing for the coronavirus for health care workers with a doctor’s order. Ball State University cancels the May commencement.
  • March 24: Indiana’s death toll rises to 29. Fred Payne of Indiana Workforce Development says any Hoosiers out of work, including temporary layoffs, are eligible to apply for unemployment benefits.
  • March 25: Indiana’s death toll rises to 35. Indianapolis Motor Speedway announces the Indianapolis 500 is moved to Aug. 23.
  • March 26: Indiana’s death toll rises to 44.
  • March 27: Indiana’s death toll rises to 47.
  • March 28: Indiana’s death toll rises to 58.
  • March 29: Indiana’s death toll rises to 76.
  • March 30: Indiana’s death toll rises to 91.
  • March 31: Indiana’s death toll rises above 100, to 113. Gov. Holcomb extends the limits of bars and restaurants to offer only “to go” and “carryout” through April 6. Indiana health commissioner Dr. Kristina Box, asked about when Indiana will be in a surge of COVID-19 cases, says she thinks the surge is starting.
  • April 1: Officials extend Marion County’s “stay at home” order through May 1. Marion County health officials say they will start COVID-19 testing services for front-line employees.
  • April 2: The state announces K-12 schools will be closed for the rest of the school year. The Indiana High School Athletic Association cancels spring sports seasons.
  • April 3: Gov. Holcomb extends the “stay at home” order through April 20. The state receives a federal Major Disaster Declaration for all 92 counties. The Indiana National Guard says it, the Army Corps of Engineers and state health officials will begin to assess sites for alternate health care facilities.
  • April 4: Indiana’s death toll rises above 200.
  • April 6: The state reports a Madison County nursing home has had 11 deaths. Gov. Holcomb extends the “stay at home” order through April 20. He also limits additional businesses to carry-out only.
  • April 7: Indiana’s death toll rises above 300. Indiana health commissioner Box says four long-term care facilities have 22 deaths that appear to be related to COVID-19.
  • April 10: ISDH said 24 residents of a long-term care facility in Madison County have died from COVID-related illness.
  • April 11: Indiana’s death toll rises above 400.
  • April 14: Indiana’s death toll rises above 500.
  • April 16: Indiana records more than 10,000 positive coronavirus tests. The governor says he expects Indiana to experience a reopening in early May.
  • April 17: Indiana’s death toll rises above 600. The governor says that he will extend the “stay at home” order through May 1.
  • April 20: Indiana’s death toll rises above 700. Gov. Holcomb extends the “stay at home” order to May 1. The governor also says, if the medical supply chain is in good shape, other elective medical procedures can resume April 27.
  • April 22: Indiana’s death toll rises above 800. The Tyson facility in Logansport voluntarily closes so 2,200 employees can be tested for COVID-19.
  • April 24: Indiana’s death toll rises above 900. The Indianapolis City-County Council approves $25 million to help small businesses. Fishers City Council creates a city health department with a plan to test every resident.
  • April 25: ISDH says it will launch an antibody testing study for Hoosiers; thousands of residents were randomly selected to participate in the study.
  • April 27: Indiana’s death toll rises above 1,000.
  • April 28: Indiana officials say they will open COVID-19 testing to more Hoosiers, with expanded criteria and new testing services at 20 sites around the state.
  • April 29: The state says it will spent $43 million on contact tracing.
  • April 30: Indianapolis extends its stay-at-home order through May 15.
  • May 1: Gov. Holcomb announces a phased reopening plan for the state of Indiana. He also extends the stay-at-home order to May 4.
  • May 3: Indiana records more than 20,000 positive coronavirus tests.
  • May 4: Indiana enters Stage 2 of its Back on Track plan, which excludes Cass County until May 18, and Lake and Marion counties until May 11.
  • May 6:The state begins testing for all Hoosiers at 20 sites, with plans to expand the number of sites to 50 in a week. Ivy Tech Community College says it will continue virtual classes when summer courses begin in June. 
  • May 8: Cris Johnston, director of the Office of Budget and Management, says the state missed out on nearly $1 billion in anticipated April revenues; all state agencies will be given budget-cutting goals. Purdue University OKs plans to reopen for the fall semester with social distancing and other safety measures.
  • May 10: Indiana’s death toll rises above 1,500.
  • May 13: The first phase of a state-sponsored study of the coronavirus estimated about 186,000 Hoosiers had COVID-19 or the antibodies for the novel virus by May 1. Indianapolis Mayor Joe Hogsett announced plans for limited reopenings of worship services, retail establishments, libraries and restaurants.
  • May 15: Simon Property Group reopens Castleton Square Mall, Circle Centre Mall, and Fashion Mall at Keystone
  • May 18: Indiana reports its first case of multisystem inflammatory syndrome in a child. The Farbest Foods turkey-processing plant in Huntingburg is closed for three days; 91 people had tested positive there.
  • May 21: Indiana records more than 30,000 positive coronavirus tests.
  • May 22: Indiana advances to Stage 3 of the Back on Track reopening plan. Indianapolis closes portions of five streets to allow restaurants to reopen with outdoor dining only.
  • May 27: Indiana University says the fall semester will have in-person and online courses, plus an adjusted calendar through May 2021. Ball State University says the fall semester will be 13 straight weeks of in-person classes with no day off on Labor Day and no fall break.
  • May 28: Indiana’s death toll rises above 2,000.
  • May 29: Places of worship in Marion County can begin holding indoor services at 50% capacity with proper social distancing. Jim Schellinger, Indiana secretary of commerce, said the federal Paycheck Protection Program has made 73,430 loans in Indiana totaling $9,379,164,461, the federal Economic Injury Disaster Loan program has made 5,070 loans in Indiana totaling $445,428,500, and the federal Economic Injury Disaster Loans Advance program has made 38,365 grants in Indiana totaling $136,554,000.
  • June 1: Marion County restaurants begins serving customers indoors and outdoors with 50% capacity. Marion County salons, tattoo parlors reopen by appointment only. Marion County gyms, fitness centers and pools reopen with 50% capacity and no contact sports. However, a Marion County curfew that began the night of May 31 and continued into the morning of June 3 after rioting impacted the reopening of some businesses.
  • June 3: Phase 2 of statewide testing of random Hoosiers by the Indiana University Richard M. Fairbanks School of Public Health at IUPUI and the Indiana State Department of Health begins.
  • June 5: Indiana reports May tax revenues were 20% short of projections made before the coronavirus closings started.
  • June 8: Indianapolis leaders agree to spend $79 million in coronavirus relief funding on contact tracing, rent relief, personal protective equipment and support for small businesses.
  • June 12: Indiana, excluding Marion County, advances to Stage 4 of reopening plan.
  • June 15: Casinos and parimutuel racing reopen in the state. Marion County’s public libraries begin a phased reopening.
  • June 19: Marion County advances to Stage 4 of state’s reopening plan.
  • June 24: The governor says the state’s moratorium on the eviction on renters will be extended through July. Indiana announces it will create a rental assistance program July 13. Indiana Pacers guard Malcolm Brogdon says he has tested positive for COVID-19.
  • June 27: Indiana hospitalizations for COVID-19 begin to increase, with about 33 new patients a day through July 1.
  • July 1: Indiana’s death toll rises above 2,500. The governor pauses Stage 5 final reopening plan, announces Stage 4.5 from July 4-17.
  • July 4: Indiana’s Stage 4.5 reopening plan begins.
  • July 9: Indiana records more than 50,000 positive coronavirus tests. Marion County mandates mask-wearing.
  • July 10: Indianapolis Public Schools announces its reopening plans.
  • July 11: Indy Eleven resumes 2020 season with victory at Lucas Oil Stadium. The Children’s Museum of Indianapolis reopens.
  • July 13: Indiana begins rental assistance program for all counties but Marion County. Marion County begins its own rental assistance program.
  • July 15: Indiana announces the Stage 4.5 reopening plan will continue another two weeks. The WNBA season begins.
  • July 16: Indianapolis suspends applications for its rental assistance program due to overwhelming demand.
  • July 24: Bars, taverns and nightclubs in Indianapolis are shut down again. City officials also return to other previous restrictions.
  • July 25: Indiana Fever begins WNBA season after delays.
  • July 27: Indiana governor’s order to wear face coverings begins. Great Lakes Valley Conference, which including University of Indianapolis, postpones most fall sports, including football, men’s and women’s soccer, and volleyball, until spring.
  • July 30: NBA season resumes.
  • Aug. 4: Indianapolis Motor Speedway announces the Aug. 23 Indianapolis 500 will be run without fans.
  • Aug. 5: With more than 1,000 positive tests reported in a single day, Indiana jumps to a total of 70,993 positive coronavirus tests.
  • Aug. 10: Indiana records more than 75,000 positive coronavirus tests.
  • Aug. 17: Indianapolis Public Schools restarts with online-only classes. News 8 learns the 2021 NBA All-Star Game will not happen on Presidents Day weekend in 2021.
  • Aug. 20: Indiana’s death toll rises above 3,000. Purdue University suspends 36 students after a party at a co-op.
  • Aug. 21: Indiana high school football season begins with some teams not playing due to COVID-19 concerns.
  • Aug. 23: Butler University tells undergraduates that instruction will occur remotely for the first two weeks of the semester, starting Aug. 24, instead of in classrooms.
  • Aug. 24: Purdue, Indiana, IUPUI and Ball State universities resume in-person classes.
  • Aug. 25: Reports say a fraternity, a sorority and a cooperative house at Purdue University are under quarantines.
  • Aug. 26: Gov. Holcomb extends the mask mandate through Sept. 25. Indiana’s rental assistance program will take applications for one last day.
  • Aug. 27: Indiana University says eight Greek houses are under 14-day quarantines.
  • Sept. 2: Indiana University tells 30 Greek houses in Bloomington to quarantine.
  • Sept. 6: Indiana records more than 100,000 positive coronavirus tests.
  • Sept. 8: Marion County allows bars and nightclubs to reopen with 25% capacity indoors and 50% capacity outdoors.
  • Sept. 12: The Indianapolis Colts open their season with a loss in a Jacksonville stadium with a limited number of fans.
  • Sept. 21: The Indianapolis Colts home opener is limited to 2,500 fans.
  • Sept. 23: Gov. Eric Holcomb extends the mask mandate through Oct. 17.
  • Sept. 24: The state’s mask mandate is extended through Oct. 17.
  • Sept. 25: The Mid-American Conference announces it will start a six-game football season Nov. 4, with the championship game Dec. 18 or 19.
  • Sept. 26: Indiana advances to a revised Stage 5 of Indiana Back on Track plan with relaxed limits on gatherings, restaurants, bars, nightclubs and more. Marion, Monroe and Tippecanoe counties decided to have more restrictive limits, however.
  • Sept. 27: The Indianapolis Colts second home game is limited to 7,500 fans.
  • Sept. 28: Purdue University says it’s suspended 14 students, including 13 student-athletes, for violations of a pledge designed to curb the coronavirus pandemic on campus.
  • Sept. 30: The Indiana State Department of Health’s online coronavirus dashboard began showing data on positive coronavirus cases in Indiana schools.
  • Oct. 1: IU’s website shows two additional fraternities and a sorority at the Bloomington campus have been issued “cease and desist” orders.
  • Oct. 2: Franklin College suspends classes and moves to virtual education and activities through Oct. 9 after a “concerning and unusual” increase in the positivity rate for COVID-19.
  • Oct. 3: Indiana records more than 125,000 positive coronavirus tests.
  • Oct. 4: Indiana’s death toll rises above 3,500.
  • Oct. 12: Franklin College returns to in-person classes.
  • Oct. 13: Indianapolis-based drugmaker Lilly pauses its trial of a combination antibody treatment for coronavirus for safety reasons.
  • Oct. 14: Indiana health commissioner Dr. Kristina Box announces she has tested positive for COVID-19.
  • Oct. 15: Gov. Holcomb issues executive order to extend mask mandate and Stage 5 reopening plan.
  • Oct. 18: The Indianapolis Colts third home game was limited to 12,500 fans.
  • Oct. 19: Indiana records more than 150,000 positive coronavirus tests.
  • Oct. 23: The Big Ten begins its football season.
  • Oct. 26: Indiana’s death toll rises above 4,000.
  • Oct. 29: Indiana records more than 175,000 positive coronavirus tests.
  • Oct. 30: Gov. Holcomb extends the public health emergency through Dec. 1.
  • Nov. 1: Indiana National Guard to begin deploying to long-term care facilities to provide coronavirus assistance.
  • The Mid-American Conference football teams begins its six-game regular season.
  • Nov. 5: Indiana records more than 200,000 positive coronavirus tests.
  • Nov. 8: The Indianapolis Colts fourth home game was limited to 12,500 fans.
  • Nov. 9: Indiana’s death toll rises above 4,500.
  • Nov. 11: Indiana records more than 233,000 positive coronavirus tests.
  • Nov. 12: Indianapolis calls for schools to go to virtual learning by Nov. 30.
  • Nov. 14: Indiana records more than 251,000 positive coronavirus tests.
  • Nov. 15: Indiana adds coronavirus-control restrictions for all businesses and gatherings in counties with the highest number of new cases as part of an update to the statewide COVID-19 pandemic response.
  • Nov. 16: Indiana records more than 262,000 positive coronavirus tests. Indianapolis limits capacity inside bars, private clubs, fraternal organizations and gyms to 25%; inside restaurants, libraries, funeral homes, swimming pools and shopping malls’ food courts to 50%; and inside religious services to 75%. Marion County Health Department requires preregistration for COVID-19 testing after increased demand at three drive-thru locations.
  • Nov. 18: Indiana records more than 275,000 positive coronavirus tests.
  • Nov. 20: Indiana’s death toll rises above 5,000.
  • Nov. 21: Indiana’s death toll rises above 5,100.
  • Nov. 22: Indiana records more than 300,000 positive coronavirus tests.
  • Nov. 23: Indiana’s death toll rises above 5,200. Indiana records more than 306,000 positive coronavirus tests. Indianapolis Public Schools returns to virtual learning through Jan. 18.
  • Nov. 24: Indiana records more than 312,000 positive coronavirus tests. The NCAA men’s and women’s basketball seasons begin; some games had no fans in the stands.
  • Nov. 25: Indiana’s death toll rises above 5,300. Indiana records more than 318,000 positive coronavirus tests.
  • Nov. 26: Indiana records more than 324,000 positive coronavirus tests. Butler University men’s basketball cancels Nov. 29 game against Eastern Illinois after a positive COVID-19 test.
  • Nov. 27: Indiana’s death toll rises above 5,400. Indiana records more than 328,000 positive coronavirus tests.
  • Nov. 28: Indiana records more than 333,000 positive coronavirus tests. Butler University men’s basketball team postponed two more games because of a positive COVID-19 test.
  • Nov. 29: Indiana records more than 338,000 positive coronavirus tests.
  • Dec. 2: Indianapolis ends its rental assistance program.
  • Dec. 12: Indiana’s mask mandate is set to expire.
  • Dec. 22: NBA to start league’s 75th season, delayed and shortened to a 72-game schedule because of the coronavirus pandemic.

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