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Moderna begins testing omicron-matched COVID shots in adults

FILE - In this Dec. 15, 2020, file photo, a sign for Moderna, Inc. hangs on its headquarters in Cambridge, Mass. The U.S. is poised to give the green light as early as Friday, Dec. 18, to a second COVID-19 vaccine, a critical new weapon against the surging coronavirus. Doses of the vaccine developed by Moderna Inc. and the National Institutes of Health will give a much-needed boost to supplies as the biggest vaccination effort in the nation’s history continues. (AP Photo/Elise Amendola, File)

CAMBRIDGE, Mass. (AP) — Moderna has begun testing an omicron-specific COVID-19 booster in healthy adults.

The company announced Wednesday that the first participant had received a dose. Earlier this week, competitor Pfizer began a similar study of its own reformulated shots.

It’s not clear whether global health authorities will order a change to the vaccine recipe in the wake of the hugely contagious omicron variant. The original vaccines still offer good protection against death and severe illness. Studies in the U.S. and elsewhere show a booster dose strengthens that protection and improves the chances of avoiding even a milder infection.

Moderna pointed to a small study published in the New England Journal of Medicine on Wednesday that showed antibodies able to target omicron persisted for six months after a booster dose, although the levels were dropping.

Moderna’s new study will enroll about 600 people who already have received either two doses of the company’s original shots or two plus a booster dose. All the volunteers will receive a dose of the experimental omicron-matched version.