The first round of the Big Ten tournament tipped off Wednesday in Chicago.
Michigan State coach Tom Izzo used nearly 5 minutes of his news conference following the Spartans' 72-72 victory to explain why Crean should keep his job after this season.
IU has been nearly perfect at home this season.
Indiana and Michigan are trying to get their Big Ten seasons headed in the right direction after struggling of late.
The Hoosiers lost their previous two games by double digits and were playing for the fourth time in nine days.
The Boilermakers clamped down on the Big Ten's best scoring team by harassing Indiana's shooters into tough shots and poor decisions, as Purdue ran away from its biggest rival 83-67.
Crean said that the 6-foot-7 forward will miss the rest of the season even though he continues to progress from a brain injury sustained Nov. 1.
Freshman D'Angelo Russell scored 22 points and added 10 assists for his second double-double of the season and the Buckeyes (16-5, 5-3 Big Ten) knocked off No. 23 Indiana 82-70 in front of 17,322 fans at Value City Arena for their first winning streak in conference play.
Indiana forward Hanner Mosquera-Perea is out indefinitely after injuring his right knee in practice.