INDIANAPOLIS (WISH) — Hoosiers are postponing vacations and rethinking spring break plans amid warnings of a probable coronavirus pandemic from top U.S. health officials.

Alex Kutin, the owner of Travel Leaders Indy, a travel agency on the northeast side of Indianapolis, said several local clients had rescheduled flights to China.

Chinese officials reported 406 new confirmed cases of coronavirus on Tuesday, bringing the total number of cases in mainland China to more than 78,000.

Travel agency clients from Indianapolis had also contacted Kutin with concerns about upcoming trips to Italy, he told News 8.

Italian officials reported a 45% increase in infections over the course of a single day. By Tuesday afternoon, at least 322 cases of coronavirus had been confirmed in Italy, the largest outbreak outside of Asia.

“It’s top of mind for all clients,” Kutin said of coronavirus fears. “Some of the clients are really talking about maybe canceling their plans to Italy.”

Footage obtained by a News 8 affiliate shows deserted streets and waterways in once-crowded tourist destinations in northern Italy.

Some clients are also hesitant to book cruise trips, according to a travel agent at Kutin’s business.

A woman from Logansport, Ind. was among hundreds of passengers on the Diamond Princess cruise ship infected with coronavirus.

Kutin began tracking and distributing daily updates from public health officials in an effort to keep travelers from seeking information from unreliable sources.

“We keep up with what is prescribed by the [World Health Organization (WHO)] and the [Centers for Disease Control and Prevention (CDC)],” he told News 8. “Twice a day, we get the most current updates.”

He and his wife, co-owner Geneva Kutin, are familiar with working amid widespread travel fears. The two have served “probably thousands” of clients over a travel career spanning more than 25 years, they said.

“Remember the Zika virus? And Ebola?” said Kutin. “People tend to panic. There’s no need to panic now.”

During a briefing Tuesday afternoon, CDC officials warned Americans to prepare for the inevitable spread of coronavirus in the U.S.

“The data over the past week about the spread in other countries has raised our level of concern and expectation that we are going to have ‘community spread’ here,” said Dr. Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases.

“Disruption to everyday life might be severe,” she added.