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Best Mounjaro Alternatives for Weight Loss: Natural OTC Tirzepatide Substitutes to Lose Weight

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Mounjaro is considered to be an effective prescription injection that has helped thousands of Type 2 diabetic patients live healthier lives. While it is mainly used to regulate the blood sugar levels in the body, Mounjaro is also famous for prompting a quick weight loss process.

The problem arises when people start considering Mounjaro for only their weight loss needs, even when they do not have Type 2 diabetes.

Doing so can make your body vulnerable to deadly side effects, so it is better to use safe alternatives.

What Are The Side Effects Of Tirzepatide (Mounjaro Injections)?

Common side effects of Tirzepatide may include nausea, vomiting, diarrhea, and abdominal discomfort. These gastrointestinal symptoms often occur when starting the medication but tend to improve over time as the body adjusts. Additionally, some individuals may experience headaches or dizziness.

Less common but more severe side effects may include hypoglycemia (low blood sugar) when combined with other diabetes medications, pancreatitis (inflammation of the pancreas), and changes in kidney function.

Communicate any concerning symptoms to your healthcare provider promptly.

As with any medication, the benefits and risks of Tirzepatide should be discussed with a healthcare professional, and its use should be closely monitored to ensure optimal diabetes management while minimizing potential side effects.

The Best Mounjaro Alternatives To Lead A Healthier Life in 2023

Let us explore the top 5 Mounjaro alternatives that might be worth your consideration:

  • PhenQ
  • Liv Pure
  • GlucoTrust
  • GlucoBerry
  • AlpiLean

PhenQ: Best Mounjaro Alternative To Burn Fat Naturally

  • Ingredients Used: Capsimax Powder, Chromium Picolinate, Caffeine, Nopal Cactus, L-carnitine fumarate, Innoslim, B-Vitamins, Iodine, etc.
  • Cost:
    • Pack of 1 bottle: $69.99
    • Pack of 2+1 bottles: $139.99
    • Pack of 3+2 bottles: $209.99
  • Brand: PhenQ
  • Refund Policy: 60-day money-back guarantee

PhenQ: A Brief

According to thousands of reviews, PhenQ is one of the best weight loss supplements. Its 100% natural ingredients and unique formula combine to deliver outstanding fat loss results within a short duration. The contents of this supplement are also vegan-friendly.

Several aspects of PhenQ make it an effective fat-loss supplement, mainly within its core ingredients. Its formula consists of the unique a-lacy’s reset, scientifically proven to promote body fat loss. PhenQ is suitable for any adult who is not pregnant, breastfeeding, or on any other medication.

How Does PhenQ Help?

The formula of PhenQ mainly works on the premise of destruction and prevention. Firstly, it destroys the accumulated fat inside your body – even the stubborn fat cells! Then, it prevents such buildups so you do not find yourself in the same situation again.

The prevention is carried out through various methods, including appetite suppression, reduced cravings, and higher energy levels. When you do not have the uncontrollable urge to eat junk food, you will not subject your body to the harmful fats that degrade your health over time.

Further, the higher energy levels will ensure you are motivated to exercise. When you are not tired and lazy, you might move more – precisely what your body needs to eliminate the fat buildup!

Pros Of PhenQ

There are several pros of PhenQ, such as:

  • Decent discounts on bulk purchases
  • Natural ingredients used to create the formula
  • Free shipping in the USA
  • Thousands of happy customers

Cons Of PhenQ

There are a few cons of PhenQ as well, such as:

  • Expensive as compared to similar weight loss supplements on the market

Liv Pure: Best Mounjaro Alternative To Detox Your Liver For Weight Loss

  • Ingredients Used: Berberine, Betaine, Sylimarin, Molybdenum, Glutathione, etc.
  • Cost:
    • Pack of 1 bottle: $69
    • Pack of 3 bottles: $147
    • Pack of 6 bottles: $234
  • Brand: Liv Pure
  • Refund Policy: 60-day money-back guarantee

Liv Pure: A Brief

If you have been trying to diet and exercise yet cannot lose fat – the main culprit might be your unhealthy liver. Several researchers agree that optimal liver functioning is crucial for losing weight because it consists of cells that convert food into energy, not fat reserves.

However, with the excessive amount of processed food we consume today, the health of our liver is compromised. Liv Pure aims to help people deal with this issue, mainly by cleansing and detoxifying the organ from the core.

The formula of this supplement consists of a liver fat-burning complex, which can help boost your body’s metabolism and fat-burning mechanism.

How Does Liv Pure Help?

Since the primary function of your liver is to flush the toxins from your body and break down food into energy, Liv Pure aims to optimize the functioning of this vital internal organ.

You see, over time, livers undergo several wear and tear as well as toxin buildup. This supplement mainly detoxifies the organ and helps it eliminate harmful substances. After that, the liver may find it easier to revert to normal functioning.

When it does, you might observe several health benefits, such as faster metabolism, less buildup of body fat, and a significant improvement in overall health.

Pros Of Liv Pure

Liv Pure has several pros, and a few of them are:

  • The basic premise behind the formula of Liv Pure is rooted in the power of nature
  • Ingredients used are plant-based
  • Non-GMO
  • Free of dairy and soy
  • There is no potential for habit-forming as long as you stick to the suggested dosage

Cons Of Liv Pure

There are a few cons of Liv Pure as well, like:

  • The results of Liv Pure can vary from one person to another

GlucoTrust: Best Mounjaro Alternative To Lose Weight In Your Sleep

  • Ingredients Used: Gymnema sylvestra, biotin, chromium, manganese, licorice root, cinnamon, zinc, juniper berries, etc.
  • Cost:
    • Pack of 1 bottle: $69
    • Pack of 3 bottles: $177
    • Pack of 6 bottles: $294
  • Brand: GlucoTrust
  • Refund Policy: 180-day money-back guarantee

GlucoTrust: A Brief

Suppose you want to try Mounjaro to balance your blood sugar levels and lose weight simultaneously. In that case, it is understandable that most natural supplements cannot match its efficiency. However, the side effects Mounjaro can have on your body are not worth taking a risk, so you can consider going for GlucoTrust instead.

GlucoTrust is a popular health supplement that can balance your blood sugar levels to normal and help you eliminate unwanted weight gain. It also reduces cravings and can help you sleep better.

How Does GlucoTrust Help?

One of the several ways GlucoTrust can help you lose weight is by promoting better sleep. It is a well-known fact that our body goes into a “repair” mode when we are sleeping – which also happens to be the perfect time to burn fat and rejuvenate your body. This supplement aims to help you achieve peak health by promoting better sleep quality.

Further, GlucoTrust can also improve your blood circulation – which means that your organs will get a better supply of oxygen. As a result, you will feel more energetic throughout the day. The reviews of this product also report that it has boosted the metabolism and improved the cognitive health of thousands of users.

Pros Of GlucoTrust

GlucoTrust has several pros, such as:

  • A unique blend of 15 different herbs to promote weight loss and improve overall health naturally
  • Decent discounts when purchased in bulk
  • No significant side effects were reported
  • Three free bonus products

Cons Of GlucoTrust

GlucoTrust has a few cons as well, like:

  • You may have to consume GlucoTrust for a few months to observe visible results

GlucoBerry: Best Mounjaro Alternative To Balance Sugar Levels

  • Ingredients Used: Premium Maqui Berry Extract, Chromium, Biotin, Gymnema Leaf, etc.
  • Cost:
    • Pack of 1 bottle: $59
    • Pack of 3 bottles: $147
    • Pack of 6 bottles: $234
  • Brand: MD Process
  • Refund Policy: 180-day money-back guarantee

GlucoBerry: A Brief

If you are tired of dealing with high blood sugar levels even after eating the smallest atom of sweets, yet people around you seem to gobble up their desserts and still stay healthy – you must stop blaming yourself.

Several studies by reputed organizations like Harvard tell us how blood sugar levels are affected by the blood sugar drain system of the kidneys. GlucoBerry, unlike most other supplements on the market, considers this and thus promotes healthy sugar levels in the body.

Some people even consider this doctor-formulated supplement to work just as well as Mounjaro, minus the deadly side effects.

How Does GlucoBerry Help?

The main objective of the blood sugar drain system in your kidneys is to retrieve the excess sugar in your insulin. After that, it flushes this sugar into your urine, thus pushing it out of your body.

While most blood sugar-balancing supplements claim to only work by improving insulin sensitivity, it is not enough. The blood sugar drain in your kidneys needs to work just as well, precisely what GlucoBerry aims to do.

Further, GlucoBerry does not have only one active ingredient but five core components that combine to boost your overall health by balancing your blood sugar levels.

Pros Of GlucoBerry

GlucoBerry has several pros that help it stand out, such as:

  • Unique formula that is focused on flushing sugar out of your body
  • 100% natural ingredients that are also clinically backed
  • Created in an FDA-certified facility
  • Free of soy, dairy, eggs, nuts, and crustacean
  • Non-GMO

Cons Of GlucoBerry

Here are a few cons of GlucoBerry:

  • Some reviews report that this supplement is not of much help for issues like inflammation

AlpiLean: Best Mounjaro Alternative To Balance Inner Temperature For Weight Loss

  • Ingredients Used: Golden Algae, Dika Nut, Drumstick Tree Leaf, Bigarade Orange, Turmeric Root, Ginger Root, etc.
  • Cost:
    • Pack of 1 bottle: $59
    • Pack of 3 bottles: $147
    • Pack of 6 bottles: $234
  • Brand: AlpiLean
  • Refund Policy: 90-day money-back guarantee

AlpiLean: A Brief

There are several reasons why people experience unwanted weight gain, ranging from hormonal issues to slow metabolism. Going for supplements that target the root cause is the best way to begin your weight loss journey. But wait – how will you find the root cause?

It is simple – if you have already tried everything and nothing seems to be working, the issue might be your body’s internal temperature. If you think this might be the case, you must try AlpiLean to deal with it.

It is almost impossible to know your internal body temperature at the moment as it is not as simple as checking the overall temperature with a thermometer. However, issues like constant weight gain despite taking relevant weight loss measures can imply a dip in this temperature.

The creators of AlpiLean wanted to help people achieve an average internal temperature again so that their weight loss efforts could be fruitful. This supplement comprises six alpine plants, which can ultimately help you sculpt your dream body.

How Does AlpiLean Help Lose Weight?

To understand how AlpiLean can help you lose weight, you must know the importance of maintaining an average internal temperature. When your body’s internal temperature falls in the normal range, it will burn fat at a decent pace – which will help you stay in shape.

However, if this internal temperature dips, you might lose the ability to burn fat as quickly as it accumulates. As a result, the rate of fat accumulation might take over the fat-burning rate, leading to an unwanted weight gain in your body.

But AlpiLean can prevent this situation altogether. This supplement is the ultimate blend of natural alpine ingredients proven to help people balance their internal temperatures, thus boosting their metabolism.

Pros Of AlpiLean

AlpiLean comes with a plethora of pros, like:

  • Created in an FDA-certified facility and is GMP-approved
  • Non-GMO
  • 100% natural and plant-based ingredients used to create the formula
  • Free of soy and dairy
  • Rigorous third-party inspections to prevent the supply of faulty batches

Cons Of AlpiLean

There are a few cons of AlpiLean as well, like:

  • People over the age of 35 may have to consume AlpiLean for up to 6 months to start noticing visible results

What Is It Inside The Best Mounjaro Alternatives That Makes Them Work?

The most straightforward answer to this question is “ingredients.” The ingredients of any supplement make or break them. Thus, below, we shall delve into the various natural ingredients present in the best Mounjaro alternatives and the science behind them:


Molybdenum is a trace mineral found in certain foods that has potential health benefits for fat burning and reducing fat accumulation. A recent study showed that molybdenum supplementation at a high dose (1000 mcg/day) for 12 weeks significantly decreased body fat by 17.8%. This reduction was even higher among participants who were overweight, with an average decrease of 19.7% when combined with exercise.

This ingredient in the best Mounjaro alternatives allows cells to expend fewer reserves during respiration, resulting in lowered levels of lactate buildup from carbohydrate consumption – meaning more efficient oxidation of pyruvate from glucose molecules by enzymes such as pyruvate dehydrogenase complex (PDHC).

This process requires much energy expenditure while increasing oxygen demand on our bodies, leading us down an eventual path towards weight loss as our metabolic rate moves faster through its cycle with better posed cellular integrity under its effects – allowing us to eventually reach desired physical goals much sooner than we would otherwise be able to achieve them by ourselves alone!

Milk Thistle

One of the fundamental mechanisms through which milk thistle promotes fat burning is its ability to enhance liver function. Milk thistle contains a flavonoid compound called silymarin, which has been found to have hepatoprotective properties.

This means it can protect the liver from damage caused by various factors, such as toxins and oxidative stress. By improving liver function, milk thistle helps optimize the body’s metabolic processes, including the breakdown and utilization of fats.

Another intriguing mechanism by which milk thistle may promote fat burning is its potential effects on insulin resistance. Studies have suggested that milk thistle may help improve insulin sensitivity, allowing for better regulation of blood sugar and potentially aiding in fat loss.

Maqui Berries

One of the critical mechanisms of maqui berries in supporting healthy blood glucose levels is their high content of anthocyanins. Anthocyanins are potent antioxidants that give maqui berries their vibrant purple color. By enhancing insulin sensitivity, maqui berries may aid in glucose uptake by cells, reducing the risk of high blood sugar levels.

A study conducted in 2015 provides further evidence for the effects of maqui berries on blood glucose levels and appetite suppression. The study, published in the Journal of Medicinal Food, aimed to evaluate the impact of maqui berry extract on postprandial glycemia (blood sugar levels after a meal) and satiety in healthy individuals.

The study results showed that participants who consumed the maqui berry extract experienced significantly lower postprandial glycemia than those who took the placebo. The maqui berry extract also increased feelings of fullness and reduced hunger compared to the placebo group.

Licorice Root

Licorice root contains a compound called glycyrrhetinic acid, which has been found to possess anti-obesity properties. This compound inhibits the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), crucial in converting inactive cortisone to active cortisol in fat cells.

Cortisol, also known as the stress hormone, is associated with increased fat accumulation, especially around the abdominal area. By inhibiting the activity 11β-HSD1, licorice root helps reduce cortisol levels, thereby preventing excessive fat accumulation.

A study investigating the effects of licorice root on fat burning and excess fat accumulation yielded promising results. The study involved participants with a high body mass index (BMI) and abdominal obesity.

The study found that participants in the licorice root extract group had an average reduction in BMI of 4.2% and a decrease in waist circumference by 3.8%. These results demonstrate the significant impact of licorice root on burning fat and reducing excess fat accumulation in the body.


One of the critical mechanisms by which caffeine promotes fat burning is its ability to stimulate the release of adrenaline. Adrenaline, also known as epinephrine, is a hormone that triggers the breakdown of stored fats into free fatty acids, which can then be used as an energy source by the body.

When consumed, caffeine acts as an adenosine receptor antagonist, blocking the action of adenosine, a neurotransmitter that promotes relaxation and drowsiness. This leads to increased release of adrenaline, which activates fat breakdown.

In addition to its effects on adrenaline release and thermogenesis, caffeine also can improve exercise performance. It has been shown to enhance endurance, reduce perceived exertion, and increase fat oxidation during physical activity.

This means consuming caffeine before a workout can help you exercise more intensely and for longer durations, leading to more significant calorie expenditure and fat loss.

The Best Mounjaro Alternatives To Lead A Healthier Life in 2023 Conclusion

Now that we have gone through the top 5 natural alternatives of Mounjaro, we hope you will find an option that works just as well as the injection.

As Mounjaro is known to balance blood sugar levels and promote weight loss, we included the best supplements that can offer similar benefits without side effects.

If you are on any medication, you must consult your doctor before consuming the recommended natural alternatives. None of these options suit pregnant women and children, so keep that in mind!

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The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.