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Best Nootropics to Use (Rankings Update) Top Natural Brain Booster Supplements That Work

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Nootropic supplements, also known as brain supplements or smart drugs, are dietary supplements that work as cognitive enhancers. They help to improve memory and cognitive function and boost brain energy. These particular nutritional supplements are often used by individuals struggling to maintain their brain health and looking for a brain pill to do the same.

These dietary supplements comprise various natural brain health-boosting compounds, including amino acids, vitamins, herbs, and others. They are available in multiple forms, like pills, capsules, powders, and drinks. While some of the most common use caffeine, bacopa monnieri, others use omega-3 fatty acids, ginseng, and others.

Research suggests that nootropic supplements have various mental benefits, including improved cognitive function, memory retention, reduced stress, and peak mental performance. Though, it is essential to remember that the effects of nootropic supplements can vary from person to person depending on various factors. While some people may experience significantly improved cognitive performance, others may not notice any results.

Following is the list of popular and effective nootropic supplements that will help to counter a cognitive decline in several ways:

  • Mind Lab Pro
  • NooCube
  • Oweli Neuro
  • Performance Lab Mind
  • Onnit Alpha Brain
  • Nuzena Neuro Focus+
  • Ageless Brain
  • Hunter Focus
  • Nootrogen
  • Nooceptin
  • Vyvamind

Mind Lab Pro

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: Maritime Pine Bark Extract, Bacopa monnieri, Rhodiola Rosea Extract, Citicoline, Lion’s Mane Mushroom, L-Theanine, etc.
  • Pricing: $69
  • Money-Back Guarantee: 14-day
  • What’s Unique About It: Mind Lab Pro is one of the unique brain supplements that help to counter age-related cognitive decline.

Mind Lab Pro is one of the most-sought brain supplements on the market. This natural nootropic has been created by renowned researcher Dave Wright who has the vision to create a brain supplement that would address all the symptoms like Alzheimer’s disease and sleep deprivation that can impact your brain health.

This unique cutting-edge non-GMO formula with several cognitive benefits has been prepared after years of clinical research in an FDA-registered facility.

Benefits Of Mind Lab Pro

  • The brain pill helps to improve memory and boost your cognitive abilities.
  • It improves mental processing speed and helps to enhance brain function.
  • It levels up your brain performance.
  • It protects and supports your brain health.

How Does Mind Lab Pro Work?

It is universal knowledge that the human brain is constantly changing, regenerating, and evolving, making it essential to keep them healthy and functioning. With Mind Lab Pro, you can achieve this goal by cutting down brain fog and supporting brain cell regeneration. Hence, ensuring your good cognitive health and mental function even in extreme situations.

This nootropic supplement and its blend of 11 natural ingredients target and improve your brain chemicals and helps combat age-related cognitive decline. The potent combination of amino acids, bacopa monnieri, pine bark extract, and many others works together to bring your mental function to the optimal level.


  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: Alpha GPC, Huperzine A, Cat’s Claw Extract, Bacopa Monnieri, Astragalus, Oat Straw, L-Tyrosine, Ginkgo Biloba, Resveratrol.
  • Pricing: $60
  • Money-Back Guarantee: 60-day
  • What’s Unique About It: It is one of the unique natural nootropics that helps you achieve a razor-sharp focus.

NooCube is one of the prevalent names in the market regarding nootropic supplements. Prepared in an FDA-registered facility, it is known to boost brain chemicals and counter cognitive impairment.

It is non-GMO and gluten-free, hence, entirely safe for your consumption. With its daily use, you can achieve many excellent results that you won’t find with any other nootropic supplement.

Benefits Of NooCube

  • It helps to give you mental clarity and boost your focus.
  • The dietary supplement boosts your memory retention.
  • It helps to boost mental energy.
  • This is one of the unique cognitive enhancers that protects your eyes from blue light.
  • It promotes healthy brain function by inhibiting brain fog.

How Does NooCube Work?

According to scientific evidence, lutein and two distinct zeaxanthin isomers derived from the marigold plant help to support cognitive function. It has been demonstrated by several studies that carotenoids can improve the mental performance of specific areas of the brain that are responsible for information processing.

Moreover, this is one of the unique nootropic supplements that contain carotenoids that supports brain-derived neurotrophic factor (BDNF). BDNF is a crucial memory molecule that helps to safeguard nerve cells and eliminate slow cognitive decline by supporting healthy brain functions like enhanced memory, eyesight, and others.

Oweli Neuro

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: DMAE, Biotin, Glutamic Acid, Vitamins and Minerals, Green Tea Extract, Bacopa Extract, and more.
  • Pricing: $59.99
  • Money-Back Guarantee: 100-day
  • What’s Unique About It: It is one of the unique nootropic supplements or smart drugs that provides you with healthy brain cells.

Oweli Neuro is one of the uniquely formulated nootropic supplements produced in an FDA-registered facility. It is a mix of handpicked ingredients known for enhancing cognitive functions and supporting multitasking ability for decades. This brain health-enhancing supplement contains the goodness of the powerful compound ‘huperzine A,’ a popular memory supplement.

Benefits Of Oweli Neuro

  • The nootropic supplement helps to promote multitasking ability.
  • It elevates your mood and fights off stress.
  • It helps to fight age-related cognitive decline.
  • It supports memory retention.

How Does Oweli Neuro Work?

Containing various nutrients from ingredients like bacopa monnieri, zinc, magnesium, and others, the nootropic supplement helps support your overall brain health. It improves your memory retention ability and reduces the risk of harmful diseases that can cause cognitive decline, like Alzheimer’s.

Indeed, this is one of the highly regarded and trusted brain health-boosting supplements that have been designed under careful measures. It supports your overall brain health and ensures it is free from mental fatigue.

Performance Lab Mind

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 30
  • Ingredients: Citicoline, Phosphatidylserine, L-Tyrosine, Maritime Pine Bark Extract.
  • Pricing: $59
  • Money-Back Guarantee: 30-day
  • What’s Unique About It: It is one of the unique brain supplements that help to reduce recovery time from intense mental fatigue.

Performance Lab Mind is a popular name in the market for brain supplements. Its efficient and unique cognitive function-boosting formula helps you achieve optimal brain health without involving artificial components. Its unique combinations of natural nootropics ingredients help you unlock the full potential of your brain chemicals and reach peak brain performance in any situation.

Benefits Of Performance Lab Mind

  • This brain supplement helps to improve memory and learning.
  • It helps cognitive abilities and boosts mental processing speed.
  • It supports your mental performance in adverse situations.
  • The brain pill helps to improve brain health.

How Does Performance Lab Mind Work?

With its effective blend consisting of pine bark extract and several vitamins, this brain pill helps to boost your overall brain health.

Its cutting-edge brain health-boosting formula helps you maintain sharp concentration and mental clarity and sustain optimal brain performance even in adverse situations. It is a brain pill that helps promote smooth neuro-nutrient delivery to enhance overall cognitive function.

Unlike other brain supplements in the cognitive function-boosting arena, Performance Lab Mind has been exclusively designed to enhance and optimize all aspects of your cognitive function.

Onnit Alpha Brain

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 90
  • Ingredients: L-Tyrosine, L-Theanine, Cat’s Claw, Oat Straw, Bacopa Monnieri, and more.
  • Pricing: $79.95
  • Money-Back Guarantee: 90-day
  • What’s Unique About It: It is one of the unique nootropics and smart drugs that helps to boost mental alertness with its high-quality ingredients.

Consisting of natural nootropics like bacopa monnieri, oat straw, and others, Onnit Alpha Brain is one of the popular nootropic supplements. The company behind Alpha Brain is Onnit Labs which Joe Rogan, a famous personality in the health market, owns.

It is one of the renowned nootropics manufacturer companies that has held the reputation of being the best for years. It has produced many products, and Alpha Brain is one of them.

Benefits Of Onnit Alpha Brain

  • With its nerve growth factor, it helps to improve cognitive function.
  • It helps in enhancing your mental performance.
  • It helps to boost mental clarity and improve memory.
  • It supports cellular integrity and boosts mental alertness.

How Does Onnit Alpha Brain Work?

Alpha Brain is one of the comprehensive smart drugs that contain a particular blend designed to increase the production of alpha brain waves. Prepared under strict conditions in an FDA-registered facility, this brain health-enhancing formula is known to do wonders, like providing you with improved cognitive performance.

Having gone through several clinical tests and trials for its ability to release alpha brain waves, the supplement is entirely safe for your use. It helps in improving brain function and verbal memory recall among several users.

Nuzena Neuro Focus+

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: DMAE, Vitamins, Minerals, Bacopa Monnieri, Folic Acid, Biotin.
  • Pricing: $45
  • Money-Back Guarantee: 30-day
  • What’s Unique About It: It is a unique nootropic supplement that helps improve cognitive functions through the goodness of bacopa monnieri.

Formulated with clinically proven ingredients, Nuzena Neuro Focus+ is one of the popular nootropic supplements that help to boost mental energy. It has been prepared in an FDA-approved facility and has followed every purity standard needed to improve cognitive health. Its gluten-free and sustainably sourced formula is known to do wonders for your brain health without triggering any negative responses.

Benefits Of Nuzena Neuro Focus+

  • The supplement helps to improve your mental clarity.
  • It boosts your cognitive health.
  • It helps to boost memory.
  • It helps to boost cognitive abilities.

How Does Nuzena Neuro Focus+ Work?

You can easily hit your mental equilibrium by consuming two capsules of this nootropic supplement. The goodness of bacopa monnieri and other essential vitamins helps improve blood flow towards your brain and helps to deal with mental fatigue. Its unique blend consists of organic elements that help to improve brain function effectively.

Ageless Brain

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: Dragon’s Blood Resin Extract, Bacopa Monnieri, Cat’s Claw, Camu Camu, Cinnamon, and more.
  • Pricing: $69
  • Money-Back Guarantee: 14-day
  • What’s Unique About It: It is one of the unique nootropic supplements that help improve blood flow to the brain and mental performance.

Ageless Brain is a potent formula designed to support mental clarity, focus, memory, and brain energy. It is called a nootropic powerhouse, containing a blend of three powerful components: bacopa monnieri, cat’s claw, and Sangre de Drago. All these three are natural and effective solutions for supporting brain health and work for all ages.

Benefits Of Ageless Brain

  • This nootropic supplement helps to give you a boost of mental energy.
  • It helps in reducing brain fog.
  • It helps to prevent cognitive decline.
  • The supplement helps to improve the health of brain cells.

How Does Ageless Brain Work?

The fact that makes this nootropic supplement different from other prescription drugs is that it has been designed chiefly for older adults. Its potent blend of eight organic herbs and botanical elements makes it perfect for protecting your brain health. The supplement guarantee purity and potency of its formula. Hence, it is entirely safe for your intake.

Moreover, it has no artificial additions and boosts your brain cells with energy and clarity.

Hunter Focus

  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 180
  • Ingredients: Maritime Pine Bark Extract, Bacopa monnieri, Rhodiola Rosea extract, Citicoline, Lion’s Mane Mushroom, L-Theanine, L-Carnitine, Vitamins, Ashwagandha, Caffeine Anhydrous, Ginkgo Biloba, Spanish Sage, Panax Ginseng and more.
  • Pricing: $90
  • Money-Back Guarantee: 14-day
  • What’s Unique About It: It is a popular nootropic supplement that reduces mental fatigue.

Created by Roar Ambition, Hunter Focus is one of the prevalent names in the health market for boosting brain function. Established in 2012, Roar Ambition is a renowned company with a reputation for supplying its customers with an extensive range of potent products that provide several physical and mental health benefits.

The supplement is prepared in an FDA-registered facility and contains bacopa monnieri, which is known to support healthy brain function.

Benefits Of Hunter Focus

  • The supplement helps to boost your cognitive health.
  • It supports your mental function.
  • It supports healthy brain cells and promotes mental energy.
  • It improves your creativity.

How Does Hunter Focus Work?

With its blend of carefully handpicked vitamins, minerals, and amino acids, Hunter Focus has been designed to improve brain function naturally. It works by nourishing your brain cells with essential vitamins and nutrients that help you to remain energetic and creative throughout your day.

Hunter Focus has got you covered in all aspects. Whether you want to remain concentrated at work or study, it does the job for you. This prescription drug’s daily intake helps improve memory and deliver the support you need to achieve all your desired goals.


  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: Glutamic acid, L-tyrosine, Amino Acids, DMAE, Biotin, Magnesium, Zinc.
  • Pricing: $29.95
  • Money-Back Guarantee: 30-day
  • What’s Unique About It: It is one of the best nootropic supplements that help to improve memory and boost mental energy.

As we all know that nootropic is a highly sought-after supplement that provides crucial nutritional support to enhance various cognitive functions such as memory, concentration, motivation, mood, and overall thought patterns. Nootrogen is a well-known name in the industry and is known for its unique formula for boosting mental energy through a particular formula.

Benefits Of Nootrogen

  • The dietary supplement helps to improve memory.
  • It supports your concentration levels.
  • It helps to reduce mental fatigue and improve brain function.

How Does Nootrogen Work?

Nootrogen is a holistic approach to enhancing cognitive performance and providing adequate sleep. Its blend consists of essential amino acids, vitamins, and minerals that help to restore healthy cognitive function.

It is one of the best nootropic supplements, smoothens the blood flow to the brain, and helps you to achieve peak mental performance without worrying about the negative impacts.


  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: Citicoline, Rhodiola Rosea, Bacopa Monnieri, L-Theanine, Lion’s Mane Mushroom, Panax Ginseng.
  • Pricing: $69
  • Money-Back Guarantee: NA
  • What’s Unique About It: It is one of the best nootropic supplements that help to reduce your stress and anxiety.

Nooceptin is one of the prevalent names in the brain supplement market. Formulated by SAP Nutra, this formula is of high quality and incredibly potent. Its blend is made of all-natural ingredients backed by scientific research. Unlike other nootropics that contain synthetic compounds, Nooceptin is a safe and effective alternative to smart prescription drugs, providing a natural boost to cognitive function without the risk of harmful side effects.

Benefits Of Nooceptin

  • The supplement helps to boost your long-term memory.
  • It helps to boost brain power.
  • It helps to reduce stress and anxiety.
  • It protects your brain cells.
  • It sharpens your brain and focuses.
  • It also improves blood flow to the brain.

How Does Nooceptin Work?

The blend of natural ingredients in Nooceptin is designed to support overall mental health and cognitive function. Bacopa Monnieri and Ginkgo Biloba are well-known for enhancing memory and concentration, while Phosphatidylserine has been shown to improve overall cognitive function. N-Acetyl-L-Tyrosine is a precursor to dopamine and is involved in synthesizing catecholamines, which play a role in mood and motivation.

The daily consumption of this mental energy-boosting supplement has received positive feedback from its users, who have reported improvements in cognitive abilities, memory recall, focus, and motivation after using the product for just a few weeks.


  • Product Category: Natural Nootropic Supplements
  • Product Form: Capsules
  • Servings Per Container: 60
  • Ingredients: Vitamin B6 – 2.5 mg, Vitamin B12 – 50 mcg, L-Tyrosine – 300 mg, Citicoline – 200 mg, L-Theanine – 150 mg, Caffeine Anhydrous – 75 mg.
  • Pricing: $74.99
  • Money-Back Guarantee: 30-day
  • What’s Unique About It: It is one of the best nootropic supplements for boosting cognitive health in high-performing adults.

Vyvamind is a cutting-edge company that offers a unique “over-the-counter neuro stimulant” product designed to enhance focus and clarity for high-performance individuals. The product is marketed explicitly towards professionals such as programmers, traders, pilots, surgeons, and students who require intense concentration and focus.

Benefits Of Vyvamind

  • It provides you with unparalleled focus and mental clarity.
  • It increases your motivation and drive.
  • It helps to reduce stress and boosts your cognitive health.
  • It boosts your mental energy.
  • It helps to counter attention deficit hyperactivity disorder.

How Does Vyvamind Work?

Vyvamind’s proprietary blend contains a powerful combination of natural ingredients clinically tested and demonstrated to enhance cognitive and physical performance and reduce brain fog. With its unique formula and targeted approach, Vyvamind stands out as a top choice for individuals seeking a safe and reliable supplement to support their mental and physical performance.

It also helps to counter attention deficit hyperactivity disorder, which is very common in most people.

Scientific Evidence-Backing Ingredients In The Best Nootropic Supplements

Let us now have a look at some of the common natural ingredients found in efficacious nootropic supplements and how they are backed by science:

Maritime Pine Bark Extract

Maritime Pine bark extract (Pycnogenol®) is a natural plant extract sourced from the bark of Pinus pinaster, a tree indigenous to the coastal areas of southwestern France. Pycnogenol® is rich in powerful antioxidants and offers numerous health benefits, including reduced inflammation, enhanced blood circulation, strengthened blood vessels, and improved cognitive function and brain health.

Maritime Pine bark extract contains potent anti-inflammatory ingredients that have been proven to reduce inflammation in the body, which can interfere with proper cognition of facts and information. Studies have shown that regularly taking Maritime Pine Bark Extract can help improve alertness and focus and promote better learning ability.

Further studies have shown that taking 1 – 2 mg/day of Pycnogenol® for 12 weeks increased attention performance, spatial working memory, and executive functions such as planning/problem-solving skills, all related to improved cognitive function.


L-theanine is a naturally occurring amino acid found in green tea leaves and certain mushrooms like maitake and shiitake. It’s known for its calming effects on the mind and body; hence why it’s so popularly used by many people today to alleviate stress and anxiety and even promote better sleep quality.

Although the exact mechanisms of action are still unclear, research has shown that I-theanine helps lower levels of stress hormones like cortisol while raising levels of serotonin – a neurotransmitter known to produce feelings of happiness and well-being.

Research suggests that l-theanine works mainly by interacting with neurotransmitters such as GABA (γ‐aminobutyric acid), which has calming effects on the brain; glutamate, an excitatory neurotransmitter responsible for learning and memory; dopamine, an essential arousal-related substance; acetylcholine, a vital plasticity related molecule associated with long term potentiation; Norepinephrine which is involved in alertness and cognition.

Ginkgo Biloba

Ginkgo biloba is a tree indigenous to mainly southeastern China. Its leaves are commonly used in traditional Chinese medicine to treat memory loss and other aging-related issues, such as dizziness and tinnitus (ringing in the ears).

It also boasts potent antioxidant properties due to its flavonoid content, further promoting brain health and helping neutralize damaging free radicals.

A study conducted in 2018 showed that when administered over 18 months, Ginkgo biloba could improve nerve fiber connections by strengthening communication between neurons.

This effect was especially noticeable in older participants who experienced a more significant cognitive decline than younger ones.

Another 2016 meta-analysis revealed that taking ginkgo biloba can reduce inflammation within brain regions responsible for regulating emotions and moods, like dopamine receptors – thus protecting against mental fatigue or depression.

Additionally, because it acts as an antioxidant, it helps reduce oxidative stress, which is associated with age-related degenerative diseases such as Alzheimer’s disease or stroke.


Ashwagandha (Withania somnifera) is an ancient herb believed to rejuvenate the mind and body. It is primarily found in India but also other parts of South Asia. The name Ashwagandha means “the smell of a horse,” referring to the intense aroma that emanates from its roots when powdered.

Ashwagandha appears to boost cognition by directly affecting levels of critical neurotransmitters. Its unique mix of compounds includes alkaloids, which modify dopamine activity at the synapse; saponins called withanolides, which modulate gamma-aminobutyric acid (GABA); and phytosterols like stigmasterol which interact with serotonin receptors.

These chemical interactions increase alertness while promoting calmness throughout the body. Additionally, Ashwagandha can reduce inflammation throughout the body through its antioxidant properties and positively influence gene expression associated with better mental focus and resilience against stressors.


DMAE is an organic compound commonly found in fish like sardines and anchovies. It’s considered a ‘cognitive enhancer’ because it has been found to increase the production of acetylcholine, a neurotransmitter responsible for memory formation and recall in the brain.

Acetylcholine also plays a vital role in motor control, oxygenation of cells, and healthy immune function! Unlike other cognitive-enhancing supplements such as Noopept or piracetam, you don’t need to worry about serious side effects when using DMAE.

When taken orally as a supplement, DMAE breaks down into dimethylethanolamine (DMEA), entering the bloodstream and reaching the brain.

Once inside the brain, it increases levels of acetylcholine – which functions as a messenger molecule between neurons – resulting in improved brain communication, which can positively affect many aspects of cognition, from learning capacity to focus and concentration.


Choline supports our cognitive function by playing an essential role in maintaining cellular integrity throughout the body’s organs. It helps form phosphatidylcholine, vital cell membrane integrity of both nerve and non-nerve cells.

A study published in Prostaglandins Leukotrienes & Essential Fatty Acids demonstrated that participants that were given choline supplements for 14 days significantly improved their scores on several tests measuring memory recall and reaction time compared to those who did not receive supplementation at all.

Moreover, recent research suggests that choline’s ability to create essential fatty acids helps us engage more easily with social situations, which might support better overall mental health outcomes (Redwood et al., 2020). So no matter if you need help remembering names or reducing feelings of anxiety while speaking at parties—choline may be just what you need!


GABA (gamma-aminobutyric acid) is an inhibitory neurotransmitter that helps regulate neural excitation. Unlike excitatory neurotransmitters such as glutamate, which stimulates or activates nerve cells, GABA calms or silences nerve impulses by increasing its levels within the brain and peripheral nervous system. Mediating neuronal activity plays a vital role in preserving healthy cognitive function.

Studies have shown that getting enough GABA may benefit those looking to increase their memory and focus abilities.

Several studies suggest that taking oral supplements may facilitate learning processes by increasing alpha-wave activity in the brain. Alpha waves help alertness and focus by directing more attentional resources toward a task.

Other studies have noted that supplementing with GABA can reduce the time needed to remember items and improve working memory performance.


Citicoline is a compound made up of two molecules: choline and cytidine. Choline is an essential nutrient for heart and liver health, while cytidine plays a role in synthesizing phosphatidylcholine—the main component of cell membranes.

One study conducted on humans at the University of Liege’s Cognitive Neurology Unit in Belgium found that citicoline improved scores relating to short-term visual–verbal recognition memory significantly more than a placebo was able to do.

Another double-blind study published in Psychopharmacology examined how people taking either a 1200 mg dose or 400 mg dose once every day for seven days performed on multiple tests related to neurology; results showed that those who took 1200 mg had statistically significant improvements over those who just took 400 mg or placebo.

Bacopa Monnieri

Bacopa monnieri, or Brahmi, is an Ayurvedic medicinal herb native to India. In traditional Indian medicine (Ayurveda), it has been used for centuries as a “brain tonic” to promote mental clarity and enhance cognitive health. The leaves are usually dried out before being made into tablets or capsules and taken orally for brain stimulation.

Scientific studies into the effects of Bacopa monnieri have revealed several positive benefits on cognition, such as improved memory retention, emotional well-being, focus, comprehension of complex concepts, and decision-making accuracy.

These results are attributed to active components such as bacosides A and B, which are said to increase synaptic activity in the nervous system, resulting in increased production of chemicals that help with memory consolidation, mood stability, and smoothness coordination between neural functions.

Lion’s Mane Mushroom

Lion’s Mane Mushroom is an edible fungus that grows on dead hardwood trees in North America and Asia. The species takes its name from the shape of its bright white head, which resembles that of a lion’s mane. Traditional Chinese medicine has long used it to treat digestive issues, fatigue, poor circulation, nerve pain, stress-induced insomnia, stomach ulcers, and dementia.

The most exciting benefits of Lion’s Mane Mushroom lie in its ability to affect brain chemistry and neurological functioning positively.

Its active compounds can penetrate the blood-brain barrier, stimulating nerve growth factor (NGF) proteins that create new neural connections between neurons. NGF is essential in maintaining proper nervous system function, including memory formation and recall.

It is believed that an increase in NGF production via supplementation with Lion’s Mane may help reduce age-related memory decline or help treat certain neurodegenerative types of dementia such as Alzheimer’s Disease & Parkinson’s Disease.


Caffeine is a stimulant drug commonly found in coffee, tea, chocolate, energy drinks, and some medications. It belongs to a family of compounds called methylxanthines which interact with our body on a cellular level creating an exaggerated physiological response in which specific processes become heightened. This produces various effects, such as increased alertness and motivation and enhanced physical performance levels due to higher adrenaline production.

Studies have shown that regular moderate caffeine intake can improve cognitive functioning through increased alertness and memory recall. Researchers believe this may be because Caffeine stimulates neurotransmitters like dopamine that transmit information between neurons (nerve cells).

Caffeine also increases glucose metabolism rates in our brains and provides a “jolt” of energy that can translate into greater focus and attentiveness toward tasks.

Vitamin C

Vitamin C (or ascorbic acid) is an essential vitamin found mainly in fruits and vegetables. It has multiple roles in the body and is involved in tissue growth repair, iron absorption, fat metabolism, and cell division. Vitamin C is also a powerful antioxidant that protects cells from damage caused by free radicals. It can be taken orally or applied topically.

Studies suggest that vitamin C may provide cognitive health benefits by promoting learning and memory formation, reducing oxidative stress markers, and protecting against neurodegenerative diseases such as Alzheimer’s disease.

One study published in Frontiers in Nutrition showed that vitamin C supplements improved cognition, specifically working memory. Another study published in Nutritional Neuroscience linked regular supplementation with better mental performance during verbal fluency tests.

How Did We Rank The Best Nootropic Supplements?

Following are the ranking factors we considered to rank the best nootropic supplements to enhance the human brain:

Clinical Trials And Research

Clinical studies are research-backed supplements that tell you a lot about your nootropic supplement. It ensures that the supplement has been scientifically tested and proven effective. Clinical trials involve rigorous testing on human subjects and are considered the gold standard for evaluating the safety and efficacy of supplements.

Clinical trials provide researchers with data on the optimal dosage and formulation of the ingredients to achieve the desired effects. This means that some of the best nootropic supplements made after clinical trials are more likely to contain the right amount of active ingredients like ginkgo biloba, increasing the chances of effectiveness.

Medical Board Approved

By choosing doctor-approved nootropic supplements, you can also reduce the risk of adverse reactions or interactions with other medications or health conditions that you may have. It is always a good idea to consult a healthcare professional before starting any new supplement or medication.

Looking for doctor-approved nootropic supplements is important because doctors can provide professional advice and guidance on what supplements are safe and effective for you to use. A doctor can assess your health needs and advise you on the best nootropic supplements to prevent cognitive decline and improve memory and overall brain chemicals.

Honest Benefits

Nootropic supplements with genuine benefits will have clear and realistic claims about their effects, dosages, and potential side effects. This information can help you decide whether the supplement suits your needs and goals. Choosing a nootropic supplement with real benefits also ensures you are not wasting money on products that do not deliver the promised results.

Choosing supplements that have been transparently and accurately labeled with the ingredients and their amounts is essential. This way, you can ensure that you are getting what you paid for and that the ingredients are safe, effective, and backed by scientific research.

Third-Party Testing

Third-party testing always provides you with vital details about the supplement. You get to know thoroughly about the quality of the product, its ingredients, and potential side effects. It also helps in verifying the components and purity of a nootropic supplement.

Through this, you will also know all the parameters the supplement fulfills and if it will provide you with the needed cognitive benefits.

Natural Ingredients

To ensure a supplement is trustworthy, its ingredients must have clinical support demonstrating their effectiveness through multiple studies. Additionally, the components must be dosed in a manner supported by clinical research.

From herbal supplements to essential vitamins and amino acids, a wide variety of natural nootropics can be safely incorporated into your daily routine. So, fuel your brain with the proper nutrients and unlock your full cognitive potential with nootropics that nourish and have a peak mental performance.

FAQs About Nootropics

Q: What Is The Function Of The Nootropics?

A: The function of nootropics is to enhance cognitive function, which includes memory, focus, concentration, creativity, motivation, and overall brain wellness.

Nootropics support the brain’s natural functions, such as regulating neurotransmitters, increasing blood flow and oxygenation, and protecting brain cells from damage caused by toxins and stress. Nootropics can also help to improve mood and reduce anxiety, which can further improve cognitive function.

The exact function of a specific nootropic can depend on its unique blend of ingredients and the intended purpose of the supplement. Nootropics aim to safely and effectively improve brain function, helping individuals achieve better cognitive performance and overall wellness.

Q: Who Are Nootropic Supplements For?

A: Brain supplements are generally for anyone looking to enhance their cognitive, memory, focus, and mental health. They may benefit individuals with demanding jobs or tasks requiring high levels of mental clearance, such as students, professionals, athletes, and creative professionals.

Additionally, these supplements benefit older adults who want to maintain or improve their brain abilities as they age.

Q: How Long Does It Take For A Nootropic Supplement To Work?

A: The time it takes for a nootropic supplement to show results can vary depending on the individual, the specific supplement, and the desired effect. Some people may notice an immediate improvement in cognitive function, while others may take a few weeks to see any changes.

In general, nootropic supplements that work by increasing blood flow or energy levels may have a more immediate effect. In contrast, supplements that work by enhancing brain function or repairing neural pathways may take longer to produce noticeable results.

Q: Are Nootropic Supplements Safe For Everyone?

A: Brain supplements are generally safe for healthy adults but may not be for everyone. It’s essential to consult with a healthcare professional before taking any new supplement, especially if you have pre-existing medical conditions, are taking prescription medications, or are pregnant or breastfeeding.

Some individuals may also be more sensitive to certain ingredients in these supplements and may experience side effects such as headaches, insomnia, gastrointestinal distress, or allergic reactions.

However, it’s important to note that nootropic supplements do not replace a healthy lifestyle and should be used with a balanced diet, regular exercise, and good sleep habits. It’s also essential to consult with a healthcare professional before beginning any new supplement regimen.

Q: What Is Alpha Wave Activity?

A: Alpha waves are a type of brainwave frequency between 8 to 13 Hz (cycles per second). Also known as alpha rhythm, these signals are generated by the brain’s neurons when we are in an awakened but relaxed state – like daydreaming or meditating. Generally speaking, lower Hz readings indicate less active brains (e.g., deeper sleep levels), whereas higher Hz readings indicate more active brains (e.g., alertness and concentration).

Research has shown that alpha wave activity can improve focus, reduce stress and enhance creativity. In addition, alpha waves have been linked to the stimulation of serotonin production, which helps regulate mood and reduce anxiety.

Q: Can Nootropic Boosters Help Prevent Symptoms Of Early Alzheimer’s?

A: Recent studies have suggested that nootropic boosters could help prevent or delay the onset of early symptoms of Alzheimer’s disease. Nootropic substances such as cocoa flavanols and omega-3 fatty acids have been associated with improved cognitive function in individuals diagnosed with Alzheimer’s, indicating their potential as preventative agents against dementia.

Other research has suggested that regular use of cognitive-enhancing drugs may reduce the risk of developing Alzheimer’s disease later in life.

In one study conducted by researchers from the University of Missouri, participants who took 90 mg daily for one year had fewer memory deficits than their non-user counterparts. This suggests that regular use of nootropics could play an essential role in reducing an individual’s risk of developing Alzheimer’s disease later in life.

While nootropic supplements are generally safe, it is always advised to use them in moderation. Overusing them or other dietary supplements can lead to side effects like headaches, sleep deprivation, and anxiety. In conclusion, nootropic supplements are nutritional supplements that can improve cognitive health, boost brain power, and others.

Nootropic supplements can improve cognitive performance, memory, creativity, and motivation. While research has shown that some of these prescription drugs can have mental benefits, using them responsibly and in moderation is essential to avoid adverse side effects.

Also Read: Top Adderall Alternative Supplements

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